Buy cocaine online

Hello everyone. My name is Nicole and I'm a molecular biologist.

In the spring, I launched a Telegram channel on science and medicine, where I dispel various myths, review drugs and dietary supplements, and explain complex subjects in a simple way.

I've been reading Pikabu for a long time, but hadn't dared publish posts there, although my friend Pikabushnik assured me that this kind of content is appreciated here and that articles would be well received. So, under @aelir1's influence, I published my first post here. If it works, I'll publish more.

Please note: this post is purely informative and contains no appeals or propaganda.

History of cocaine

The first cocaine users were Amerindians, who chewed coca leaves, which contain cocaine. The plant was then introduced to Europe, where, in the mid-1800s, the German chemist Niemann isolated cocaine hydrochloride (cocaine in salt form). It began to be used as an anesthetic, but doctors discovered that the effects weren't limited to anesthesia, and there was a very pleasant side effect: euphoria. And people were swept away.

Little did the harmless plant know that one day it would become man's best friend.

In the 1880s, cocaine was not only considered totally harmless, but almost a universal remedy, and was sold in the form of elixirs and tonics. The most popular tonic of the time was Mariani wine - a blend of Bordeaux and cocaine that had everyone, including the Pope, hooked.

Shortly afterwards, American William Pemberton invented his own version of Mariani wine: French Wine Coca with the addition of damiana extract. Later, wine and cocaine were removed from the composition, cola nuts were added as a source of caffeine, the product was carbonated, and thus Coca-Cola was born.

Coca-Cola used to be a happy drink.

After the 1800s, cocaine use declined due to its inclusion on the list of narcotic substances. The next peak in massive use came in the 1980s. It was at this time that another, much more powerful and dangerous product appeared on the scene: freebase.

Freebase

The problem with cocaine hydrochloride is that it can't be smoked, due to the high melting point of the salt. Heating it up is no problem, but at 200°C, there's not much cocaine left. However, cocaine salt can be neutralized with a base to transform it into almost pure cocaine, which has a lower melting temperature and is suitable for smoking. This process is called freebasing.

Freebasing was not only practiced by drug dealers, but also by home users, transforming powder into smokable crystals. The danger of this process lay in the fact that highly flammable substances were used, leading to a well-known incident where famous comedian Richard Pryor accidentally burst into flames during freebasing and spent six months recovering in hospital. So people started using baking soda and water instead of flammable substances - thus obtaining crack. This method is very simple but dirty: the final product contains impurities.

Crack

Crack enjoyed a frenzied popularity among all socio-economic classes. It was a cheap product with a powerful and, above all, fast-acting effect.

When smoked, cocaine reaches the brain within 8 seconds, producing a powerful feeling of euphoria. The effect also ends quickly, and after 5 minutes, you feel normal and want to smoke again. It's an ideal scenario for drug dealers, but less ideal for the user. This mode of consumption is considered the most dangerous because of the strong dependency it engenders.

How does cocaine affect the brain?

1. Cocaine blocks the transmission of pain signals, which explains why it was first used as an anesthetic.
2. Cocaine increases the amount of dopamine and serotonin in the space between neurons.

What does this mean?

In this post, I briefly explain how the brain works (and how amphetamines and MDMA work). Here I'll explain in a little more detail.

Our brains are made up of a large number of nerve cells (neurons), and they need to exchange information for you to be a viable being. Each neuron has dendrites - short extensions that receive information - and axons, long extensions that send information. The place where the dendrite and axon meet to transmit information is called the synapse. Basically, it's an empty space.

Neuron A sends the information in the form of a bubble containing a neurotransmitter (a substance that can excite or inhibit neurons), and it travels across the space between two neurons and attaches itself to a receptor on the surface of neuron B. The B neuron receives the chemical signal (information). This signal is transformed into an electrical signal, which travels down the axon of neuron B and is transformed into a neurotransmitter, transmitted to neuron C. And so on.

The neurotransmitters released by the axons simply bind to the receptor, exciting or inhibiting the B neuron. What happens to them after signal transmission? In general, they are either destroyed by specific enzymes or returned to neuron A.

Thus, cocaine locks the "doors" of neuron A, and neurotransmitters (in particular dopamine and to a lesser extent serotonin) cannot return. The dopamine accumulates in the synapse and over-stimulates neuron B, leading to the ensuing effects.