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Yes, the "cocaine bear" did exist. Here's the story.
Nearly 40 years after the discovery of a 175-kilo black bear ingesting cocaine in a forest
Interesting facts about cocaine
Cocaine is extracted from the leaves of the coca bush, which grows in South America. Cocaine is the stimulant of
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Cocaine facts
World Cocaine Consumption
Cocaine is one of the world's most widely consumed illicit drugs, with major markets in Europe and Asia. North America and in Europe.
- North America :
- Visit United States remain the world's largest cocaine market. By 2021, around 5.2 million of people reported having used cocaine in the past year, according to the National Survey on Drug Use and Health (NSDUH).
- Although this figure is slightly lower than in 2000, consumption remains a cause for concern, particularly in large cities such as New York, Los Angeles and Miami.
- Europe :
- Cocaine consumption in Europe has increased significantly over the last two decades. According to theEuropean Monitoring Centre for Drugs and Drug Addiction (EMCDDA)approximately 3.5 million of European adults used cocaine in 2021.
- Countries with the highest consumption includeSpainthe United Kingdomthe Netherlands and theGermany. Spain, in particular, is considered the gateway to Europe for cocaine, due to its geographical proximity to South America.
- Other regions :
- Cocaine consumption is also on the rise in regions such asAustralia, l'West Africa and parts of theAsiaalthough at lower levels than in North America and Europe.
Cocaine in Culture and Society
Cocaine has a rich and complex history, deeply rooted in the indigenous cultures of South America and influencing modern popular culture.
- Traditional use :
- Coca leaves have been used for thousands of years by the indigenous peoples of the Andes for their stimulating and medicinal properties. They were chewed or brewed into tea to combat fatigue, hunger and the effects of altitude.
- Today, in Bolivia and Peru, the traditional consumption of coca leaves remains legal and an integral part of local culture.
- Influence in Popular Culture :
- Cocaine has often been glamorized in film, music and literature. Films such as Scarface (1983) and Blow (2001) have helped shape the image of cocaine as a symbol of power and rebellion.
- In music, artists like Amy Winehouse, Whitney Houston and Pablo Escobar (whose lives inspired many works) have been associated with cocaine use, reflecting its impact on society.
- Illegal markets and crime :
- The illegal cocaine trade generates billions of dollars every year, fuelling international criminal networks. According to theUNODCthe global cocaine market is estimated at more than 100 billion dollars per year.
- Violence linked to cocaine trafficking remains a major problem in producer and transit countries, such as Argentina and Brazil. Mexico and Central American countries.
The most memorable film is Blowstarring Johnny Depp.
Eric Clapton sang the song "Cocaine", the video of which you can see on youtube.
World Cocaine Report 2023
I would like to highlight the main theses of the report:
Concentration in established markets increases expansion potential.
In established cocaine markets, the proportion of the general population using the drug is high. But these markets only cover around a fifth of the world's population.
If prevalence in other regions rises to that of established markets, the number of users worldwide would increase considerably, due to the size of the underlying population.
This type of market convergence has already occurred in Western and Central Europe, where purity levels and prices have harmonized with those in the United States, although the prevalence of cocaine consumption in Western and Central Europe has not yet reached US levels.
Other points highlighted in the report
- The "Southern Cone" route becomes the main departure point for cocaine destined for Europe
- Concentration in established markets paves the way for strong expansion
- Africa's role in the global supply chain is growing
- Southeast Europe consolidates its position as a transit region
- Technological advances boost sea smuggling
Read the full report at United Nations site.
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Hello everyone. My name is Nicole and I'm a molecular biologist.
Last spring, I launched a Telegram channel dedicated to science and medicine. On this channel, I strive to demystify various concepts, carry out analyses of drugs and dietary supplements, and explain complex subjects in a clear and accessible way.
I've been a Pikabu reader for a long time, but hadn't yet dared to publish. My friend Pikabushnik assured me, however, that this type of content is appreciated here and that my articles would be well received. It's thanks to @aelir1's encouragement that I'm publishing my first post today. If it meets with a good reception, I'll be happy to share more.
Important: this post is purely informative, with no appeal or attempt at propaganda.
History of cocaine
The first users of cocaine were the Amerindians, who chewed coca leaves, where cocaine is found. The plant was then introduced to Europe, where, in the mid-1800s, the German chemist Niemann isolated cocaine hydrochloride (cocaine in salt form). It began to be used as an anaesthetic, but doctors discovered that its effects were not limited to anaesthesia, and that it had a very pleasant side effect: euphoria. And people were seduced.
Little did the harmless plant know that one day it would become man's best friend.
In the 1880s, cocaine was not only considered totally harmless, but almost a universal remedy, and was sold in the form of elixirs and tonics. The most popular tonic of the time was Mariani wine - a blend of Bordeaux and cocaine that had everyone, including the Pope, hooked.
Shortly afterwards, American William Pemberton invented his own version of Mariani wine: French Wine Coca, with the addition of damiana extract. Later, wine and cocaine were removed from the composition, cola nuts were added as a source of caffeine, the product was carbonated, and thus Coca-Cola was born.
Coca-Cola used to be a happy drink.
After the 1800s, cocaine use declined due to its inclusion on the list of narcotic substances. The next peak of massive use came in the 1980s. At the same time, another, much more powerful and dangerous product appeared: freebase.
Freebase
The problem with cocaine hydrochloride is that it can't be smoked, due to the high melting point of the salt. Heating it up is no problem, but at 200°C, there's not much cocaine left. However, cocaine salt can be neutralized with a base to transform it into almost pure cocaine, which has a lower melting temperature and is suitable for smoking. This process is called freebasing.
Freebasing was not only practiced by drug dealers, but also by home users, transforming powder into smokable crystals. The danger of this process lay in the fact that highly flammable substances were used, leading to a well-known incident where famous comedian Richard Pryor accidentally burst into flames during freebasing and spent six months recovering in hospital. So people started using baking soda and water instead of flammable substances - thus obtaining crack. This method is very simple but dirty: the final product contains impurities.
Crack
Crack enjoyed a frenzied popularity among all socio-economic classes. It was a cheap product with a powerful and, above all, fast-acting effect.
When smoked, cocaine reaches the brain within 8 seconds, producing a powerful feeling of euphoria. The effect also ends quickly, and after 5 minutes, you feel normal and want to smoke again. It's an ideal scenario for drug dealers, but less ideal for the user. This mode of consumption is considered the most dangerous because of the strong dependency it engenders.
How does cocaine affect the brain?
- Cocaine blocks the transmission of pain signals, which explains why it was first used as an anesthetic.
- Cocaine increases the amount of dopamine and serotonin in the space between neurons.
What does this mean?
In that post, I briefly explained how the brain works (and how amphetamines and MDMA work). Here, I'll explain it in a little more detail.
Our brain is made up of many nerve cells (neurons), which must exchange information if you are to be a viable being. Each neuron has dendrites - short extensions that receive information - and axons, long extensions that transmit information. The place where the dendrite and axon meet to transmit information is called the synapse. Basically, it's an empty space.
Neuron A sends the information in the form of a bubble containing a neurotransmitter (a substance that can excite or inhibit neurons), and this bubble travels across the space between the two neurons to bind to a receptor on the surface of neuron B. Neuron B receives the chemical signal (information). This signal is transformed into an electrical signal, which travels down the axon of neuron B and is converted into a neurotransmitter, transmitted to neuron C. And so on.
The neurotransmitters released by the axons simply bind to the receptor, exciting or inhibiting the B neuron. What happens to them after signal transmission? In general, they are either destroyed by specific enzymes or returned to neuron A.
Thus, cocaine blocks the "gates" of neuron A, and neurotransmitters (in particular dopamine and, to a lesser extent, serotonin) cannot return. Dopamine accumulates in the synapse and over-stimulates neuron B, leading to the effects that follow.
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However, there is a problem with this approach.
Cocaine constricts the blood vessels lining the cartilage in the nasal septum, leading to the death of the tissues supporting the tip of the nose. At first, your nose is constantly running. Then, irritation leads to tissue necrosis, and the tip of the nose collapses or becomes deformed. I haven't looked to see what it looks like, but I think it must resemble Voldemort.
Dopamine receptors are particularly abundant in the brain regions responsible for alertness, hunger, emotion, pleasure and motor activity. Cocaine consumption leads to an accumulation of dopamine in these regions, resulting in alertness, absence of hunger, increased stamina and motor activity, as well as heightened sensitivity.
The half-life of cocaine is 50 to 60 minutes (the time needed to eliminate half the substance from the body). This is very short compared to amphetamines, whose half-life is 11 to 14 hours, so the effect doesn't last long. On the one hand, this is good, because you're not under the effect of the drug for more than a day, and your body doesn't "wear out". On the other hand, because of the short-term effect, there's a temptation to take another dose.
Behind the scenes
Cocaine is a dangerous substance because of the terrible dependence it engenders.
This is explained by dopamine, which plays an essential role in the brain's reward system.
Cocaine causes a release of dopamine → the brain remembers this action as pleasurable, as its reward centers are stimulated → the brain seeks to repeat this action, driving the person to look for a way to obtain a new dose.
In addition to dependence, addiction develops, as the brain adapts to an excess of dopamine. As a result, the person consumes more and more often, hoping to feel what he or she will never be able to feel again. A vicious circle.
The more a person consumes, the more physical side effects there are:
- Problems with the nose or total disappearance of the nose
- Risk of heart attack and other cardiac and circulatory problems
- Permanent depression, psychosis, sleep disorders
- Paranoia and hallucinations (including the sensation of worms under the skin)
Taking drugs during pregnancy is particularly dangerous (who knew?), as it increases the risk of premature delivery, and the child is very likely to be born with a drug dependency. In other words, not only have you had no choice in existing, but it's unlikely that you'll be able to offer your child a normal future. From the very first moments of his life, he will have to fight to rid himself of this addiction.
But it's not all doom and gloom. It's important to remember that, to avoid all these consequences, it's necessary to seek help in time. Drug dependence is treatable, and there are many ways to restore your health and regain control of your life.
If you or a loved one is facing this problem, it's important to consult professionals who can help you every step of the way, from detox to rehabilitation. Addiction is a disease, and it can be overcome.
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